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Positive effects are weight loss and lowered blood sugar
To the right are widefield images of HeLa cells with lentivirus mediated LUC, Lb NOX, Ec STH, mito Ec STH expression under Dox control transiently expressing iNAP1, in basal medium (DMEM without pyruvate, fluorescent vitamins and phenol red with 5 mM glucose, 25 mM HEPES, pH 7.4 and 1% dialyzed FBS), or when cells were switched to the basal medium without glucose but with 10 mM pyruvate
When using it, attention should be paid to concentration control and following relevant regulations and safety guidelines
It features an arginine substitution at position 3 and an extra 13 amino acids at the N-terminus, making it about three times more potent than native IGF-1 with a half-life of 20-30 hours
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